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Benchmarking green chemistry adoption by 'big pharma' and generics manufacturers

机译:对“大型制药公司”和仿制药制造商采用绿色化学进行基准测试

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摘要

Purpose - The purpose of this paper is to benchmark current adoption of green chemistry (GC) practices by the innovative and generic pharmaceutical companies and examine the drivers, barriers and future opportunities. Design/methodology/approach - The authors examined publicly available data for the top 10 "big pharma" and top ten generic drug manufacturers. Using the IQ Green Chemistry working group framework for effective GC programs, they scored each of the 20 companies in seven key areas. Findings - The study finds that generic drug companies have not embraced GC at the level of the innovative pharmaceutical companies (average GC score of 2 vs 11 for "big pharma"). Top two barriers for them include: lack of pressure and incentives, and the burdensome regulatory process for making changes in the manufacturing process. Research limitations/implications - The research is based on publicly disclosed information. It is possible that some generic drug manufacturers have begun to work internally on GC but have not disclosed externally yet. Future research should include a survey or interviews of generic drug manufacturers. Practical implications - The company-level analysis, benchmarking framework and results are of value for researchers and practitioners interested in advancing greater adoption of GC by the pharmaceutical industry. Originality/value - This study provides the first company-level benchmarking of GC adoption by the largest innovative and generics drug manufacturers. It contributes to the literature on the barriers and drivers for greater adoption of GC.
机译:目的-本文的目的是对创新和非专利制药公司当前采用绿色化学(GC)做法进行基准测试,并研究驱动因素,障碍和未来机会。设计/方法/方法-作者检查了前十大“大型制药企业”和前十大仿制药制造商的公开数据。他们使用IQ绿色化学工作组框架进行有效的GC计划,他们在七个关键领域对20家公司进行了评分。调查结果-研究发现,仿制药公司没有在创新制药公司的水平上接受GC(“大型制药公司”的平均GC得分为2比11)。它们面临的两个主要障碍包括:缺乏压力和激励措施,以及制造过程进行更改的繁琐的监管流程。研究的局限性/含义-研究基于公开披露的信息。一些非专利药制造商可能已经开始内部研究GC,但尚未对外披露。未来的研究应包括对仿制药制造商的调查或访谈。实际意义-公司级别的分析,基准框架和结果对有兴趣推动制药行业广泛采用GC的研究人员和从业人员具有价值。原创性/价值-这项研究为最大的创新药和非专利药制造商采用GC进行了公司一级的基准测试。它为有关GC广泛采用的障碍和驱动因素的文献做出了贡献。

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