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Special issue of Atmospheric Environment for Particulate Matter: Atmospheric Sciences, Exposure, and the Fourth Colloquium on PM and Human Health

机译:涉及颗粒物的大气环境特刊:大气科学,接触和第四次PM和人类健康研讨会

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摘要

In response to epidemiological studies published over 20 years ago, at least three research communities have been intensively studying airborne particulate matter (PM). These efforts have been coordinated by approaching the source―atmospheric accumulation/receptor― exposure-dose―health effects paradigm (adopted from NRC, 2001) from different perspectives or along different parts of the paradigm. The atmospheric sciences communities consider the emissions of particles and precursors from sources, their transport and transformation in air to receptor locations, and finally removal from the atmosphere. The exposure communities' interest is to examine the pathways by which pollution or PM, in this case, approaches and enters the body, typically by trying to relate PM concentrations at a central location(s) to exposure and perhaps dose. Both the atmospheric sciences and exposure communities approach the paradigm from left to right. In contrast, the health effects communities have studied health outcomes, including hospital admissions, school absences, disease rates and deaths in human populations, and potential mechanisms of biological actions in laboratory settings. In general, the health effects communities' approach the paradigm from right to left attempting to correlate an observed adverse health effect with dose or exposure measures. For the most part, research results are reported in scientific publications and conferences for each community respectively. Over the years, there has been little effort to integrate information from these diverse groups in a substantive way. While a major attempt took place in 1998 at the Chapel Hill workshop (Albritton and Greenbaum, 1998), little has occurred since.
机译:为了回应20年前发表的流行病学研究,至少三个研究社区一直在深入研究空气中的颗粒物(PM)。通过从不同角度或沿着该范式的不同部分研究源-大气累积/受体-暴露剂量-健康效应范式(从NRC,2001年采用)来协调这些努力。大气科学界考虑了粒子和前驱物的排放源,它们在空气中的迁移和转化到受体位置,以及最后从大气中清除。暴露人群的兴趣是检查污染或PM在这种情况下进入并进入人体的途径,通常是通过尝试将中心位置的PM浓度与暴露或剂量联系起来。大气科学界和暴露界都从左到右接近范式。相反,对健康的影响社区已经研究了健康结局,包括入院,失学,人口中的疾病发生率和死亡以及实验室环境中生物行为的潜在机制。一般而言,健康影响社区从右到左采用该范例,试图将观察到的不良健康影响与剂量或接触措施相关联。在大多数情况下,研究结果分别在各个社区的科学出版物和会议中报告。多年来,几乎没有任何努力以实质性的方式整合来自这些不同群体的信息。 1998年,在教堂山(Chapel Hill)车间进行了一次重大尝试(Albritton和Greenbaum,1998年),此后几乎没有发生。

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