Electrochemical corrosion characteristics and biocompatibility of nanostructured titanium for implants

摘要

Graphical abstractSignificantly enhanced in-vitro corrosion resistance and biocompatibility to nano-grained pure titanium (Ti)Display OmittedHighlights•Nanocrystalline layer on pure Ti surface was fabricated by SFT.•Improvement of corrosion resistance for NG Ti was due to the thickness and homogeneity of passive film.•Enhancement of cellular response for NG Ti was attributed to nano-topography and higher hydrophilicity.•The improvement in anti-corrosion properties and biocompatibility of NG Ti is linked to its unique structure.AbstractIn the present study, a nano-grained (NG) surface layer on a commercial pure (Grade-2) titanium sheet was achieved by means of sliding friction treatment. The surface characteristics,in vitrocorrosion behavior and biocompatibility of NG Ti were investigated, compared with those of the conventional coarse-grained (CG) substrate. The protective passive film on NG Ti surface is thicker than that on CG Ti, leading to its enhanced biological corrosion resistance in simulated body fluid (SBF) solution. In addition, NG Ti shows a much higher hydrophilicity and nano-roughness, which is related to its significantly improved cell attachment, spreading, proliferation and maturation relative to CG Ti. The enhanced biological anti-corrosion properties and biocompatibility render NG Ti a promising biomaterial for implants.