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Compact and cost effective lab-based edge-illumination x-ray phase contrast imaging with a structured focal spot

机译:具有结构焦点的紧凑且经济高效的基于实验室的边缘照明X射线相衬成像

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摘要

We present a different implementation of the Edge Illumination (EI) X-ray Phase Contrast imaging method based on the use of multiple focal spots created through an additional x-ray mask. While this resembles directly inspired by the Talbot-Lau implementation of grating interferometry, the aim of the source mask and its effect on the acquired images are different. The individual "sourcelets" are much larger than in grating methods, and then still spatially incoherent; however, their use allows (a) exploiting cheap and large focal spot sources and (b) reducing the source spot size from the usual 70.100 μm typically used in EI to few tens of μm, which enables the realisation of more compact setups. However, in EI, multiple sources create images shifted by one detector pixel with respect to the other, imposing the use of an image restoration algorithm. Here, we show that the approach is feasible by deconvolving differential phase-contrast image profiles acquired with three separate sources, and comparing results with simulation predictions for equivalent profiles generated by a single source. We also show that this enables reducing the system length from the 2 m used so far to 1 m.
机译:我们基于使用通过额外的X射线蒙版创建的多个焦点,介绍了边缘照明(EI)X射线相衬成像方法的不同实现。尽管这直接受到Talbot-Lau光栅干涉仪实施的启发,但源掩模的目的及其对采集图像的影响却有所不同。单独的“小源”比光栅方法大得多,然后在空间上仍不相干;但是,它们的使用允许(a)利用廉价和大型的焦点源,并且(b)将源点的尺寸从EI中通常使用的通常的70.100μm减小到几十μm,从而可以实现更紧凑的设置。但是,在EI中,多个源会生成相对于另一个像素移动一个检测器像素的图像,这意味着要使用图像恢复算法。在这里,我们证明了该方法是可行的,方法是对通过三个单独来源获取的差分相位对比图像轮廓进行反卷积,然后将结果与模拟预测进行比较,以模拟由单个来源生成的等效轮廓。我们还表明,这可以将系统长度从目前使用的2 m减少到1 m。

著录项

  • 来源
    《Applied Physics Letters》 |2016年第22期|224102.1-224102.5|共5页
  • 作者单位

    Department of Medical Physics and Bioengineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom;

    Department of Medical Physics and Bioengineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom;

    Department of Medical Physics and Bioengineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom;

    Department of Medical Physics and Bioengineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom;

    Department of Medical Physics and Bioengineering, University College London, Malet Place, Gower Street, London WC1E 6BT, United Kingdom;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
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