Effectiveness of treatment with donepezil hydrochloride and changes in regional cerebral blood flow in patients with Alzheimer's disease

Tsunetaka Yoshida; Sangkil Ha-Kawa; Masafumi Yoshimura; Kenji Nobuhara; Toshihiko Kinoshita; Satoshi Sawada

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Effectiveness of treatment with donepezil hydrochloride and changes in regional cerebral blood flow in patients with Alzheimer's disease

机译：盐酸多奈哌齐的治疗效果和阿尔茨海默氏病患者局部脑血流的变化

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The objective of this study was to elucidate the relationship between the effects of donepezil hydrochloride (donepezil) and cerebral blood flow, and to evaluate the usefulness of cerebral blood flow imaging in assessing and predicting treatment effectiveness.

机译：这项研究的目的是阐明盐酸多奈哌齐（多奈哌齐）的作用与脑血流之间的关系，并评估脑血流成像在评估和预测治疗效果中的有用性。

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来源
《Annals of Nuclear Medicine》 |2007年第5期|257-265|共9页
作者
Tsunetaka Yoshida; Sangkil Ha-Kawa; Masafumi Yoshimura; Kenji Nobuhara; Toshihiko Kinoshita; Satoshi Sawada;
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作者单位

Department of Radiology Kansai Medical University 10-15 Fumizonocho Moriguchi Osaka 570-8506 Japan;

Department of Radiology Kansai Medical University 10-15 Fumizonocho Moriguchi Osaka 570-8506 Japan;

Department of Neuropsychiatry Kansai Medical University Osaka Japan;

Department of Neuropsychiatry Kansai Medical University Osaka Japan;

Department of Neuropsychiatry Kansai Medical University Osaka Japan;

Department of Radiology Kansai Medical University 10-15 Fumizonocho Moriguchi Osaka 570-8506 Japan;

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原文格式 PDF
正文语种 eng
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关键词
Donepezil; Cerebral blood flow; SPECT; Alzheimer's disease; Cognitive function;

机译：多奈哌齐;脑血流;SPECT;阿尔茨海默氏病;认知功能;

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专利

1. Donepezil hydrochloride preserves regional cerebral blood flow in patients with Alzheimer's disease. [J] . Nakano S, Asada T, Matsuda H, The Journal of Nuclear Medicine . 2001,第10期

机译：盐酸多奈哌齐可保护阿尔茨海默氏病患者的局部脑血流。
2. Donepezil Hydrochloride Preserves Regional Cerebral Blood Flow in Patients with Alzheimera€?s Disease [J] . Seigo Nakano, Takashi Asada, Hiroshi Matsuda, The Journal of Nuclear Medicine . 2001,第10期

机译：盐酸多奈哌齐可保留阿尔茨海默氏病患者的局部脑血流量
3. Changes in regional cerebral blood flow and functional connectivity in the cholinergic pathway associated with cognitive performance in subjects with mild Alzheimer's disease after 12-week donepezil treatment [J] . LiW., AntuonoP.G., XieC., NeuroImage . 2012,第2期

机译：多奈哌齐治疗12周后轻度阿尔茨海默氏病患者认知功能相关的区域脑血流量和胆碱能途径功能连接的变化
4. Cerebral perfusion patterns associated with the clinical response to donepezil therapy in Alzheimer's disease patients [C] . Haruo Hanyu, Soichiro Shimizu, Kentaro Hirao, International Symposium on Functional and Molecular Imaging of Stroke and Dementia . 2006

机译：与临床反应相关的脑灌注模式在阿尔茨海默病患者患者中的临床反应相关
5. A study of correlation between the values of the Amen Brain System Checklist and the cerebral blood flow values of SPECT scans of treatment resistant patients. [D] . Chambers, Gerard A., Jr. 2010

机译：阿门脑系统检查表的值与治疗耐药患者的SPECT扫描的脑血流值之间的相关性研究。
6. Changes in Regional Cerebral Blood Flow and Functional Connectivity in the Cholinergic Pathway Associated with Cognitive Performance in Subjects with Mild Alzheimer’s Disease after 12-week Donepezil Treatment [O] . Wenjun Li, Piero G. Antuono, Chunming Xie, -1

机译：胆碱能途径的区域脑血流和功能性连通性12周内含有轻度阿尔茨海默病患者的认知性能相关
7. Changes in regional cerebral blood flow and functional connectivity in the cholinergic pathway associated with cognitive performance in subjects with mild Alzheimer's disease after 12-week donepezil treatment [O] . Wenjun Li, Piero G. Antuono, Chunming Xie, 2012

机译：胆碱能途径的区域脑血流和功能性连通性，12周内含有轻度阿尔茨海默病患者的认知性能相关

Effectiveness of treatment with donepezil hydrochloride and changes in regional cerebral blood flow in patients with Alzheimer's disease

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