Triage Sepsis Alert and Sepsis Protocol Lower Times to Fluids and Antibiotics in the ED.

摘要

More than 1 million patients are admitted with sepsis each year in the United States; of these, nearly a quarter die, exceeding the combined mortality from breast, lung, and prostate cancer. Consequently, incresing resources are being spent toward identifying sepsis and mitigating its deadly toll. Many institutions have implemented sepsis recognition protocols to identify patients early because previous work showed that this strategy improves outcomes. This SWAT (Sepsis Workup and Treatment) trial was undertaken at the emergency department (ED) of the Medical University of South Carolina. They evaluated the efficacy of early identification, triage, and mobilization of resources for patients with sepsis. Sepsis was identified on clinical suspicion of infection with either hypotension (SWAT A) or presence of two systemic inflammatory response syndrome criteria (SWAT B) in triage. Patients meeting either category triggered a "sepsis alert," leading to rapid administration of antibiotics and intravenous fluids.