In Vitro Bioactivity Study of Pure Wollastonite Prepared from Local Raw Materials

摘要

CaSiO3 ceramics have been proposed as a medical material for artificial bone and dental root, since they proved to be bioactive and biocompatible. In this study, CaSiO3 powders were synthesized by mixing of Calcium oxide (CaO) and (SiO2) for 3 h, and subsequent calcination of the mixture at 710 degrees C for 2 h. The compacts were conventionally sintered at 1150 degrees C for 2 h. Moreover, the in vitro bioactivity of wollastonite was investigated by soaking the powders in simulated body fluid (SBF) for various time periods to analyze the nucleation and growth of hydroxyapatite (HA) on the surface of the powders. The obtained results showed that hydroxy-carbonate-apatite (HCA) can be formed on the surface of alpha-CaSiO3 particles soaked in SBF solution for 3 days, and a continuous layer of dense deposits of HCA covered the surface of alpha-CaSiO3 powders after 15 days of soaking in SBF solution. Besides this, alpha-CaSiO3 showed strong hydration when soaked in SBF solution and the hydration was favorable for formation of HCA. Finally, obtained results indicate that alpha-CaSiO3 showed to be highly bioactive through the formation of homogeneous apatite layer.