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Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer

机译：卡培他滨联合依维莫司（RAD001）在先前治疗过的转移性胃癌患者中进行的I期临床试验

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PurposeEverolimus is a novel inhibitor of the mammalian target of rapamycin pathway, which is aberrantly activated in cancer cell. We conducted a phase I study of capecitabine plus everolimus (RAD001) in refractory gastric cancer patients.

机译：目的依维莫司（Everolimus）是雷帕霉素途径的哺乳动物靶标的新型抑制剂，雷帕霉素途径在癌细胞中被异常激活。我们对难治性胃癌患者进行了卡培他滨联合依维莫司（RAD001）的I期研究。

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期刊名称 Springer Open Choice
作者
Taekyu Lim; Jeeyun Lee; Duk Joo Lee; Ha Yeon Lee; Boram Han; Kyung Kee Baek; Hee Kyung Ahn; Su Jin Lee; Se Hoon Park; Joon Oh Park; Young Suk Park; Ho Yeong Lim; Kyoung-Mee Kim; Won Ki Kang;
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作者单位

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年(卷),期 -1(68),1
年度 -1
页码 255–262
总页数 8
原文格式 PDF
正文语种
中图分类外科学;
关键词
Gastric cancer Everolimus Capecitabine;

机译：胃癌;依维莫司;卡培他滨;

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专利

1. Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer. [J] . Lim T, Lee J, Lee DJ, Cancer chemotherapy and pharmacology. . 2011,第1期

机译：卡培他滨联合依维莫司（RAD001）在先前治疗过的转移性胃癌患者中进行的I期临床试验。
2. Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer [J] . Taekyu Lim, Jeeyun Lee, Duk Joo Lee, Cancer Chemotherapy and Pharmacology . 2011,第1期

机译：卡培他滨联合依维莫司（RAD001）在先前治疗过的转移性胃癌患者中进行的I期临床试验
3. Phase II trial of capecitabine and everolimus (RAD001) combination in refractory gastric cancer patients [J] . LeeJ., LeeS.J., ParkS.H., Investigational new drugs. . 2013,第6期

机译：卡培他滨和依维莫司（RAD001）联合治疗难治性胃癌患者的II期试验
4. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
5. Clinical and Economic Outcomes for Gastric Cancer Patients Treated with Gastrectomy at Centres with and without Cancer Surgery Designation in Ontario [D] . Jeong, Yunni . 2019

机译：安大略省患有癌症手术指定胃癌治疗胃癌患者的胃癌患者的临床和经济结果
6. Randomized Open Label Phase III Trial of Irinotecan Plus Capecitabine versus Capecitabine Monotherapy in Patients with Metastatic Breast Cancer Previously Treated with Anthracycline and Taxane: PROCEED Trial (KCSG BR 11-01) [O] . In Hae Park, Seock-Ah Im, Kyung Hae Jung, 2019

机译：伊立替康联合卡培他滨与卡培他滨单药治疗以前用蒽环类和紫杉烷类治疗的转移性乳腺癌患者的随机开放标签III期试验：继续试验（KCSG BR 11-01）
7. Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer [O] . Taekyu Lim, Jeeyun Lee, Duk Joo Lee, 2011

机译：卡培他滨联合依维莫司（RAD001）在先前治疗过的转移性胃癌患者中进行的I期临床试验

Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer

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