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Joint Effects of Known Type 2 Diabetes Susceptibility Loci in Genome-Wide Association Study of Singapore Chinese: The Singapore Chinese Health Study

机译：新加坡华人全基因组关联研究中已知的2型糖尿病易感基因座的联合作用：新加坡华人健康研究

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BackgroundGenome-wide association studies (GWAS) have identified genetic factors in type 2 diabetes (T2D), mostly among individuals of European ancestry. We tested whether previously identified T2D-associated single nucleotide polymorphisms (SNPs) replicate and whether SNPs in regions near known T2D SNPs were associated with T2D within the Singapore Chinese Health Study.

机译：背景全基因组关联研究（GWAS）已确定2型糖尿病（T2D）的遗传因素，其中大多数是欧洲血统的个体。在新加坡华人健康研究中，我们测试了先前确定的与T2D相关的单核苷酸多态性（SNP）是否复制，以及在已知T2D SNP附近的区域中的SNP是否与T2D相关。

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期刊名称 PLoS Clinical Trials
作者
Zhanghua Chen; Mark A. Pereira; Mark Seielstad; Woon-Puay Koh; E. Shyong Tai; Yik-Ying Teo; Jianjun Liu; Chris Hsu; Renwei Wang; Andrew O. Odegaard; Bharat Thyagarajan; Revati Koratkar; Jian-Min Yuan; Myron D. Gross; Daniel O. Stram;
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年(卷),期 2010(9),2
年度 2010
页码 e87762
总页数 10
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专利

1. Polymorphisms Identified through Genome-Wide Association Studies and Their Associations with Type 2 Diabetes in Chinese, Malays, and Asian-Indians in Singapore [J] . Jonathan T. Tan, Daniel P. K. Ng, Siti Nurbaya, The journal of clinical endocrinology and metabolism . 2010,第1期

机译：通过全基因组关联研究确定的多态性及其与新加坡华人，马来人和亚洲印第安人的2型糖尿病的关系
2. Genome-Wide association studies-derived susceptibility loci in type 2 diabetes: Confirmation in a Chinese population [J] . Clinical and investigative medicine: Medecine clinique et experimentale . 2012,第5期

机译：全基因组关联研究得出的2型糖尿病易感基因座：在中国人群中的证实
3. Replication Study for the Association Between Four Loci Identified by a Genome-Wide Association Study on European American Subjects With Type 1 Diabetes and Susceptibility to Diabetic Nephropathy in Japanese Subjects With Type 2 Diabetes [J] . Shiro Maeda Shin-ichi Araki Tetsuya Babazono Masao Toyoda Tomoya Umezono Koichi Kawai Masahito Imanishi Takashi Uzu Hirotaka Watada Daisuke Suzuki Atsunori Kashiwagi Yasuhiko Iwamoto Kohei Kaku Ryuzo Kawamori Yusuke Nakamura Diabetes . 2010,第8期

机译：通过全基因组关联研究确定的欧美人1型糖尿病患者与日本2型糖尿病患者糖尿病肾病易感性的四个基因座关联的复制研究
4. The Empirical Study on the Relationship between Host Country Conditions and the Investment Patterns of China-Singapore Joint Ventures in China [C] . LUO Yushu, JING Runtian 第五届技术与创新管理国际研讨会 . 2007

机译：东道国条件与中新合资企业在华投资方式关系的实证研究
5. Etiology of weight change, type 2 diabetes, and mortality in adult Chinese Singaporeans: The Singapore Chinese health study. [D] . Odegaard, Andrew. 2009

机译：新加坡华人成年人体重变化，2型糖尿病和死亡率的病因：新加坡华人健康研究。
6. Diabetes mellitus and the risk of total knee replacement among Chinese in Singapore the Singapore Chinese Health Study [O] . Ying-Ying Leung, John Carson Allen, Li-Wei Ang, -1

机译：新加坡华人的糖尿病与全膝关节置换的风险新加坡华人健康研究
7. Joint effects of known type 2 diabetes susceptibility loci in genome-wide association study of Singapore Chinese: The Singapore Chinese health study [O] . Chen Z, Pereira MA, Seielstad M, 2014

机译：新加坡华人全基因组关联研究中已知的2型糖尿病易感基因座的联合作用：新加坡华人健康研究

Joint Effects of Known Type 2 Diabetes Susceptibility Loci in Genome-Wide Association Study of Singapore Chinese: The Singapore Chinese Health Study

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