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A Randomized Phase III Clinical Trial of Plecanatide a Uroguanylin Analog in Patients With Chronic Idiopathic Constipation

机译：乌拉圭林类似物Plecanatide在慢性特发性便秘患者中的随机III期临床试验

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Objectives:This study assessed the efficacy and safety of plecanatide, a guanylate cyclase-C (GC-C) agonist and the first uroguanylin analog approved for the treatment of chronic idiopathic constipation (CIC).

机译：目的：本研究评估了plecanatide，鸟苷酸环化酶C（GC-C）激动剂和首个被批准用于治疗慢性特发性便秘（CIC）的尿鸟苷类似物的疗效和安全性。

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期刊名称 NPG Open Access
作者
Philip B Miner Jr; William D Koltun; Gregory J Wiener; Marianela De La Portilla; Blas Prieto; Kunwar Shailubhai; Mary Beth Layton; Laura Barrow; Leslie Magnus; Patrick H Griffin;
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年(卷),期 -1(112),4
年度 -1
页码 613–621
总页数 9
原文格式 PDF
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专利

1. A Randomized Phase III Clinical Trial of Plecanatide, a Uroguanylin Analog, in Patients With Chronic Idiopathic Constipation [J] . Miner Philip B. Jr., Koltun William D., Wiener Gregory J., The American Journal of Gastroenterology . 2017,第4期

机译：慢性特发性便秘患者尿癌素，尿囊黄素模拟的随机期III临床试验
2. Plecanatide, a Novel Uroguanylin Analog: A 12-Week, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Trial to Evaluate Efficacy and Safety in Patients With Irritable Bowel Syndrome With Constipation (IBS-C) [J] . Miner Philip, DeLuca Robert, La Portilla Marianela, The American Journal of Gastroenterology . 2014,第Suppla2期

机译：Plecanatide，一种新型的鸟嘌呤类似物：一项为期12周，随机，双盲，安慰剂对照，剂量范围试验，用于评估便秘型肠易激综合征（IBS-C）患者的疗效和安全性
3. Randomized clinical trial: efficacy and safety of plecanatide in the treatment of chronic idiopathic constipation [J] . Michael DeMicco, Laura Barrow, Bernadette Hickey, Therapeutic advances in gastroenterology. . 2017,第11期

机译：随机临床试验：plecanatide治疗慢性特发性便秘的疗效和安全性
4. The use of the “Healthwear” wearable system in chronic patients'' early hospital discharge: Control randomized clinical trial [C] . Katsaras Th., Milsis A., Rizikari M., 5th International Symposium on Medical Information Communication Technology . 2011

机译：在慢性病患者中使用“ Healthwear”可穿戴系统”出院初期：对照随机临床试验
5. Recruitment, retention and compliance in randomized, phase III clinical trials involving obese patients diagnosed with type 2 Diabetes Mellitus with respect to weight loss practicum report. [D] . Mithani, Moez S. 2012

机译：涉及诊断为2型糖尿病的肥胖患者的有关减肥实践的随机III期临床试验中的招募，保留和依从性报告。
6. Randomized clinical trial: efficacy and safety of plecanatide in the treatment of chronic idiopathic constipation [O] . Michael DeMicco, Laura Barrow, Bernadette Hickey, 2017

机译：随机临床试验：plecanatide治疗慢性特发性便秘的有效性和安全性
7. Randomized clinical trial: efficacy and safety of plecanatide in the treatment of chronic idiopathic constipation [O] . Michael DeMicco, Laura Barrow, Bernadette Hickey, 2017

机译：随机临床试验：斑己酰胺治疗慢性特发性便秘的疗效和安全性

A Randomized Phase III Clinical Trial of Plecanatide a Uroguanylin Analog in Patients With Chronic Idiopathic Constipation

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