首页> 美国卫生研究院文献>Internal Medicine >Elevated Levels of Intelectin-1 a Pathogen-binding Lectin in the BAL Fluid of Patients with Chronic Eosinophilic Pneumonia and Hypersensitivity Pneumonitis
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Elevated Levels of Intelectin-1 a Pathogen-binding Lectin in the BAL Fluid of Patients with Chronic Eosinophilic Pneumonia and Hypersensitivity Pneumonitis

机译:慢性嗜酸性粒细胞性肺炎和超敏性肺炎患者BAL液中Intelectin-1(一种病原体结合凝集素)水平升高

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摘要

Objective Human intelectin-1 (hITLN-1) binds to galactofuranosyl residues, which are present in the microbial cell wall, but which are absent in mammalian tissues, and has been suggested to play an immunological role against microorganisms. However, the involvement of hITLN-1 in the pathogenesis of diffuse pulmonary diseases remains unknown. The aim of this study was to compare the hITLN-1 concentrations in the bronchoalveolar lavage (BAL) fluid of patients with diffuse pulmonary diseases.
机译:目的人类整合素-1(hITLN-1)与半乳糖呋喃糖基残基结合,该残基存在于微生物细胞壁中,但在哺乳动物组织中不存在,并且已被建议对微生物起免疫作用。然而,hITLN-1参与弥漫性肺部疾病的发病机制仍然未知。这项研究的目的是比较弥漫性肺部疾病患者支气管肺泡灌洗液(BAL)中的hITLN-1浓度。

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