首页> 美国卫生研究院文献>Neuro-Oncology >PDCT-17 (LTBK-11). PNOC007: H3.3K27M SPECIFIC PEPTIDE VACCINE COMBINED WITH POLY-ICLC FOR THE TREATMENT OF NEWLY DIAGNOSED HLA-A2+ H3.3K27M MIDLINE GLIOMAS

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PDCT-17 (LTBK-11). PNOC007: H3.3K27M SPECIFIC PEPTIDE VACCINE COMBINED WITH POLY-ICLC FOR THE TREATMENT OF NEWLY DIAGNOSED HLA-A2+ H3.3K27M MIDLINE GLIOMAS

机译：PDCT-17（LTBK-11）。 PNOC007：H3.3K27M特异性肽疫苗与Poly-ICLC合并用于治疗新诊断的HLA-A2 + H3.3K27M中线Gliomas

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摘要

To assess within a multi-center trial the safety of H3.3K27M specific peptide vaccine in combination with poly-ICLC in HLA-A02.01+ patients diagnosed with H3.3K27M+ diffuse midline gliomas.

机译：在多中心试验中评估H3.3K27M特异性肽疫苗的安全性与HLA-A02.01 +患者中的Poly-ICLC组合，患者诊断出患有H3.3K27M +弥漫性中线Gliomas。

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期刊名称 Neuro-Oncology
作者
Sabine Mueller; Rishi Lulla; Stewart Goldman; Anu Banerjee; Susan Chi; Nicholas Whipple; John Crawford; Karen Gauvain; Kellie Nazemi; Javad Nazarian; Jared Taitt; Payal Watchmaker; Takahide Nejo; Kaori Okada; Lisa Butterfield; Annette Molinaro; Michael Prados; Hideho Okada;
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年(卷),期 2019(21),Suppl 6
年度 2019
页码 vi284–vi285
总页数 2
原文格式 PDF
正文语种
中图分类神经病学;肿瘤学;
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1. Clinical and Radiological Response to Dabrafenib in Diffuse Midline Glioma Harbouring H3.3K27M and BRAF-V600E Mutations [J] . Biassoni V., Schiavello E., Podda M., Pediatric blood & cancer . 2019,第S4期

机译：DabrafeNib在弥漫性中线胶质瘤患H3.3K27M和BRAF-V600E突变的临床和放射响应
2. Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas [J] . PollackI.F., JakackiR.I., ButterfieldL.H., Journal of Clinical Oncology . 2014,第19期

机译：用新诊断的恶性脑干和非勃治脑膜肿瘤溶解的胶质瘤相关抗原肽和多胞聚环丁酸稳定的抗原特异性免疫应答和临床结果促使赖氨酸和羧甲基纤维素稳定
3. Phase Ⅰ/Ⅱ trial testing safety and immunogenicity of the multipeptide IMA950/poly-ICLC vaccine in newly diagnosed adult malignant astrocytoma patients [J] . Migliorini Denis, Dutoit Valerie, Allard Mathilde, Neuro-Oncology . 2019,第7期

机译：Ⅰ/Ⅱ期多肽IMA950 / poly-ICLC疫苗在初诊成人恶性星形细胞瘤患者中的安全性和免疫原性试验
4. P01.140 An H3.3K27M long peptide vaccine induces expansion of specific CD4 and CD8 T cell clones in a patient with progressive H3.3K27M-mutant midline glioma [O] . K Sahm, I Mildenberger, L Bunse, 2018

机译：P01.140 H3.3K27M长肽疫苗在患有进行性H3.3K27M突变中线神经胶质瘤的患者中诱导特定CD4和CD8 T细胞克隆的扩增
5. P01.140 An H3.3K27M long peptide vaccine induces expansion of specific CD4 and CD8 T cell clones in a patient with progressive H3.3K27M-mutant midline glioma [O] . K Sahm, I Mildenberger, L Bunse, 2018

机译：P01.140 H3.3K27M长的肽疫苗在患者中诱导患者的特异性CD4和CD8 T细胞克隆的膨胀，患有渐进的H3.3K27m-突变体中线胶质瘤

PDCT-17 (LTBK-11). PNOC007: H3.3K27M SPECIFIC PEPTIDE VACCINE COMBINED WITH POLY-ICLC FOR THE TREATMENT OF NEWLY DIAGNOSED HLA-A2+ H3.3K27M MIDLINE GLIOMAS

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