Brain Factor-7® improves learning and memory deficits and attenuates ischemic brain damage by reduction of ROS generation in stroke in vivo and in vitro

摘要

The beneficial effect of BF-7 on learning and memory impairment using an 8-arm maze test against focal cerebral ischemia. In the 10 mg/kg BF-7-ischemia group, numbers of errors are significantly reduced compared to those in the vehicle-ischemia group. The bars indicate mean ± SEM. *P < 0.05 compared with the vehicle-sham group; #P < 0.05 compared with the vehicle-ischemia group (n = 7)