Evaluation of the genetic relationship between high elevation pulmonary arterial pressure with moderate elevation with feedlot and carcass performance

摘要

In areas of high elevation, hypoxia-induced pulmonary hypertension (PH) causes right ventricle failure and can lead to manifestation of high mountain disease, often called brisket disease. The limited amount of oxygen available in areas of high elevation causes vasoconstriction in pulmonary vasculature (Farber and Loscalzo, 2004). Holt and Callan (2007) reported that approximately 5% death loss for cattle who reside in high elevation regions could be attributed to PH. Fortunately, pulmonary arterial pressure (PAP) can be used as an indicator trait which identifies cattle who have the potential to develop (PH). Neary et al. (2015) suggested that as cattle enter feedlot systems, an increase in adipose tissue and ruminal engorgement could increase PAP. Rapid weight gain and high intake of concentrate diets for cattle in feedlots cause increased work of cardiac ventricles and sustained accelerated circulation (Jensen et al., 1976).