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The Full Region of N-Terminal in Polymerase of IBDV Plays an Important Role in Viral Replication and Pathogenicity: Either Partial Region or Single Amino Acid V4I Substitution Does Not Completely Lead to the Virus Attenuation to Three-Yellow Chickens

机译：IBDV的聚合酶中N-末端的全部区域在病毒复制和致病性中起重要作用：部分区域或单氨基酸V4i取代并不完全导致病毒衰减到三黄鸡

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期刊名称 Viruses
作者
Weiwei Wang; Yu Huang; Zhonghua Ji; Guo Chen; Yan Zhang; Yuanzheng Qiao; Mengya Shi; Min Li; Teng Huang; Tianchao Wei; Meilan Mo; Xiumiao He; Ping Wei;
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作者单位

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年(卷),期 2021(13),1
年度 2021
页码 107
总页数 13
原文格式 PDF
正文语种
中图分类人体病毒学（致病病毒）;病毒（滤过性病毒）;
关键词
Infectious Bursal Disease Virus; N-terminal domain of VP1; reverse genetics technique; recombinant virus; viral replication and pathogenicity;

机译：感染性Bursal病毒;vp1的n末端结构域;反向遗传技术;重组病毒;病毒复制和致病性;

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专利

1. Yu, F., Ren, X., Wang, Y., Qi, X., Song, J., Gao, Y., Qin, L., Gao, H., Wang, X.A single amino acid V4I substitution in VP1 attenuates virulence of very virulent infectious bursal disease virus (vvIBDV) in SPF chickens and increases replication in CEF cells [J] . YuF., RenX., WangY., Virology . 2013,第2期

机译：Yu，F.，Ren，X.，Wang，Y.，Qi，X.，Song，J.，Gao，Y.，Qin，L.，Gao，H.，Wang，XA VP1中的单个氨基酸V4I取代减弱SPF鸡中极强的传染性法氏囊病病毒（vvIBDV）的毒力，并增强CEF细胞中的复制
2. Two single amino acid substitutions in the intervening region of Newcastle disease virus HN protein attenuate viral replication and pathogenicity [J] . Bin Liu, Yanhong Ji, Zhongqing Lin, Scientific reports. . 2015,第1期

机译：新城疫病毒HN蛋白插入区的两个单氨基酸取代减弱了病毒复制和致病性
3. A single amino acid at N-terminal region of the 2b protein of cucumber mosaic virus strain m1 has a pivotal role in virus attenuation [J] . Maneechoat Phoowanarth, Takeshita Minoru, Uenoyama Misa, Virus Research: An International Journal of Molecular and Cellular Virology . 2015,第Null期

机译：黄瓜花叶病毒m1株2b蛋白N端区域的单个氨基酸在病毒减毒中起关键作用
4. Investigating the roles of the JC virus agnogene and regulatory region using a naturally occurring, pathogenic viral isolate [D] . Ellis, Laura Christine 2014

机译：使用天然的病原性病毒分离株调查JC病毒致病基因和调控区的作用
5. Two single amino acid substitutions in the intervening region of Newcastle disease virus HN protein attenuate viral replication and pathogenicity [O] . Bin Liu, Yanhong Ji, Zhongqing Lin, -1

机译：新城疫病毒HN蛋白插入区的两个单氨基酸取代减弱了病毒复制和致病性
6. The Full Region of N-Terminal in Polymerase of IBDV Plays an Important Role in Viral Replication and Pathogenicity: Either Partial Region or Single Amino Acid V4I Substitution Does Not Completely Lead to the Virus Attenuation to Three-Yellow Chickens [O] . Weiwei Wang, Yu Huang, Zhonghua Ji, 2021

机译：IBDV的聚合酶中N-末端的全部区域在病毒复制和致病性中起重要作用：部分区域或单氨基酸V4i取代并不完全导致病毒衰减到三黄鸡

The Full Region of N-Terminal in Polymerase of IBDV Plays an Important Role in Viral Replication and Pathogenicity: Either Partial Region or Single Amino Acid V4I Substitution Does Not Completely Lead to the Virus Attenuation to Three-Yellow Chickens

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