Deep Learning for the Preoperative Diagnosis of Metastatic Cervical Lymph Nodes on Contrast-Enhanced Computed ToMography in Patients with Oral Squamous Cell Carcinoma

摘要

Cervical lymph node (LN) metastasis in patients with oral squamous cell carcinoma is one of the important prognostic factors. Pretreatment cervical nodal staging is performed using computed tomography (CT) as the first-line examination. However, imaging findings focused on morphology are not specific for detecting cervical LN metastasis. In this study, deep learning (DL) analysis of pretreatment contrast-enhanced CT was evaluated and compared with radiologists’ assessments at levels I–II, I, and II using the independent test set. The DL model achieved higher diagnostic performance in discriminating between benign and metastatic cervical LNs at levels I–II, I, and II. Significant difference in the area under the curves of the DL model and the radiologists’ assessments at levels I–II and II were observed. Our findings suggest that this approach can provide additional value to treatment strategies.