Up-regulation of DRAM2 promotes tolerance of bladder transitional cell carcinoma to gemcitabine

摘要

Bladder transitional cell carcinoma (BTCC) is one of the most prevalent human malignant diseases. Gemcitabine is commonly applied in the treatment of BTCC while acquired gemcitabine resistance has caused a severe impediment to recovery. This study aimed to investigate the function of in regulating gemcitabine resistance of BTCC.