According to last year’s status report on the global burden of cancer, colorectal carcinoma is a rising major medical concern with an estimated rate of over 1.8 million new patients and 881,000 cessations annually, making it the second main cause of cancer-related mortality worldwide ( ). Of all colorectal cancer patients, 40–76% will develop colorectal liver metastases (CRLM) in the course of their disease ( - ).
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