Creation of Novel Antihypertensive Agent via Structure-Activity Relationship Study on Phytochemicals towards Vasorelaxant Activity

摘要

Hypertension is defined as a persistently high force of blood flowing through the wall of blood vessels and it has been categorized by the American Heart Association into five stages according to severity. It is a known fact that even the general public terms hypertension as a silent killer in with a big number of public living with it undiagnosed. Even for those that are properly diagnosed and having regular follow-ups, there seem to always be the risk of concomitant diseases such as heart attack and stroke. Moreover, there are reports stated that hypertension is the most frequent co-morbidities in patients infected with COVID-19 that caused by the severe acute respiratory syndrome coronavirus SARS-CoV-2 which could lead to high mortality [ ].