Development and Validation of Voriconazole Concentration by LC‐MS‐MS: Applied in Clinical Implementation

机译：LC-MS-MS伏立康唑浓度的开发和验证：在临床实施中的应用

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Voriconazole (VRZ) is a triazole antifungal used for treatment of invasive fungal infection, which is a life‐threatening condition. Therapeutic drug monitoring is recommended for identifying the optimal dose in patients who have hepatic/renal impairment or reduced function of the CYP2C19 metabolizing enzyme.

机译：伏立康唑（VRZ）是一种三唑类抗真菌药，用于治疗侵入性真菌感染，这是一种危及生命的疾病。建议使用治疗药物监测来确定肝/肾功能不全或CYP2C19代谢酶功能降低的患者的最佳剂量。

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期刊名称 Journal of Clinical Laboratory Analysis
作者
Santirat Prommas; Apichaya Puangpetch; Nuttawut Jenjirattithigarn; Sumonrat Chuwongwattana; Thawinee Jantararoungtong; Napatrupron Koomdee; Siwalee Santon; Montri Chamnanphon; Chonlaphat Sukasem;
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作者单位

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年(卷),期 2017(31),1
年度 2017
页码 -1
总页数 7
原文格式 PDF
正文语种
中图分类生理学;
关键词
antifungal; applications; genetics;

机译：抗真菌;应用;遗传学;

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专利

1. Development and Validation of Voriconazole Concentration by LC‐MS‐MS: Applied in Clinical Implementation [J] . Santirat Prommas, Apichaya Puangpetch, Nuttawut Jenjirattithigarn, Journal of clinical laboratory analysis. . 2017,第1期

机译：LC-MS-MS伏立康唑浓度的开发和验证：在临床实施中的应用
2. Development and Validation of Voriconazole Concentration by LC-MS-MS: Applied in Clinical Implementation [J] . Prommas Santirat, Puangpetch Apichaya, Jenjirattithigarn Nuttawut, Journal of clinical laboratory analysis. . 2017,第1期

机译：LC-MS-MS的voriconazole浓度的开发和验证：在临床实施中应用
3. Development and validation of an LC-MS/MS method for simultaneous quantification of voriconazole and its main metabolite voriconazole N-oxide in human plasma and its clinical application [J] . Lei Meng, Yao Hongping, Dong Yalin, Journal of liquid chromatography and related technologies . 2017,第17a20期

机译：LC-MS / MS法的开发和验证用于同时定量伏立康唑及其血浆中含有磷沸石N-氧化物及其临床应用
4. Validation of an Immunoprecipitation, Digestion, and Immunoaffinity LC/MS/MS Assay for Human beta-NGF Biomarker and Implementation in Support of Clinical Trials [C] . Kathlyn M. Porter, Hendrik Neubert, Gary A. Schultz American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：验证人类β-NGF生物标志物的免疫沉淀，消化和免疫亲和性LC / MS / MS / MS测定和支持临床试验的实施
5. Development and Validation of LC?MS/MS Assay for 5-Amino-1-Methyl Quinolinium: Application to Pre-clinical Pharmacokinetic Studies [D] . Awosemo, Ololade Tosin. 2020

机译：LC的开发和验证LC？MS / MS测定对于5-氨基-1-甲基喹啉：在临床前药代动力学研究中的应用
6. Development Validation and Comparison of Two Mass Spectrometry Methods (LC-MS/HRMS and LC-MS/MS) for the Quantification of Rituximab in Human Plasma [O] . Aurélien Millet, Nihel Khoudour, Dorothée Lebert, 2021

机译：两种质谱法（LC-MS / HRMS和LC-MS / MS的比较用于定量人血浆中Rituximab的鉴定验证和比较
7. Development of procedures for sreening for, identification and/or validated quantification of herbal drugs in blood or urine using GC-MS, LC-MS or LC-MS/MS [O] . Beyer Jochen 2006

机译：开发使用GC-MS，LC-MS或LC-MS / MS筛选，鉴定和/或验证量化血液或尿液中草药的程序

Development and Validation of Voriconazole Concentration by LC‐MS‐MS: Applied in Clinical Implementation

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