Genetic variants on chromosomes 7p31 and 12p12 are associated with abnormal atrial electrical activation in patients with early‐onset lone atrial fibrillation

摘要

Abnormal P‐wave morphology ( ) has been associated with a history of atrial fibrillation ( ) in earlier studies. Although lone is believed to have substantial genetic basis, studies on associations between single nucleotide polymorphisms ( ) linked to lone and have not been reported. We aimed to assess whether s previously associated with lone (rs2200733, rs13376333, rs3807989, and rs11047543) are also linked to P‐wave abnormalities.