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An Improved Synthesis of Key Intermediate to the Formation of Selected Indolin-2-Ones Derivatives Incorporating Ultrasound and Deep Eutectic Solvent (DES) Blend of Techniques for Some Biological Activities and Molecular Docking Studies

机译：一种改进的合成关键中间体的方法该方法包括一些结合了超声和深共熔溶剂（DES）技术的Indolin-2-one衍生物的形成用于某些生物活性和分子对接研究

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期刊名称 Molecules
作者
Mohd Imran; Md. Afroz Bakht; Abida Khan; Md. Tauquir Alam; El Hassane Anouar; Mohammed B. Alshammari; Noushin Ajmal; Archana Vimal; Awanish Kumar; Yassine Riadi;
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作者单位

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年(卷),期 2020(25),5
年度 2020
页码 -1
总页数 24
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
thiazole-indole; DES; ultrasound; anti-inflammatory; analgesic; ulcerogenic; lipid peroxidation; molecular docking; DFT;

机译：噻唑吲哚;DES;超声;消炎;镇痛;促溃疡;脂质过氧化;分子对接;DFT;

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专利

1. An Improved Synthesis of Key Intermediate to the Formation of Selected Indolin-2-ones Derivatives Incorporating Ultrasound and Deep Eutectic Solvent (DES) Blend of Techniques, for Some Biological Activities and Molecular Docking Studies [J] . Mohd Imran, Md. AfrozBakht, Abida Khan, Proceedings . 2019,第1期

机译：一种改进的关键中间体与结合超声波和深的共晶溶剂（DES）混合技术的选择吲哚-2-衍生物的形成，用于一些生物活性和分子对接研究
2. Ultrasound-mediated synthesis, biological evaluation, docking and in vivo acute oral toxicity study of novel indolin-2-one coupled pyrimidine derivatives [J] . Nikalje Anna Pratima G., Tiwari Shailee V., Sangshetti Jaiprakash N., Research on Chemical Intermediates . 2018,第5期

机译：超声介导的合成，生物学评价，对接和体内急性口服毒性研究新型吲哚-2-一耦合嘧啶衍生物
3. Discovery of indolin-2-one derivatives as potent PAK4 inhibitors: Structure-activity relationship analysis, biological evaluation and molecular docking study [J] . Guo Jing, Zhu Mingyue, Wu Tianxiao, Bioorganic and medicinal chemistry . 2017,第13期

机译：发现Indolin-2-One衍生物作为有效的PAK4抑制剂：结构 - 活性关系分析，生物学评估和分子对接研究
4. Molecular docking of asymmetric cinchona alkaloids derivatives as new spectrum biological activities antidiabetic agent [C] . Teni Ernawatia, Desita Triana, Galuh Widyarti, International Symposium on Applied Chemistry . 2018

机译：非对称Cinchona生物碱衍生物作为新型谱生物活性抗糖尿病药剂的分子对接
5. Part One. Synthesis of optically active tryptophan derivatives with potential activity as indoleamine 2,3-dioxygenase inhibitors: An approach via asymmetric catalytic hydrogenation. Part Two. Design, synthesis and pharmacology of selective ligands for alpha1-containing GABA(A)/benzodiazepine receptor subtypes: SAR studies of beta-carbolines at positions -3 and -6 and their corresponding bivalent ligands. Part Three. First enantiospecific total synthesis of the important biogenetic intermediates, (+)-polyneuridine and (+)-polyneuridine aldehyde, as well as 16-epi-vellosimine and macusine A. [D] . Yin, Wenyuan. 2007

机译：第一部分。具有吲哚胺2,3-二加氧酶抑制剂潜在活性的旋光色氨酸衍生物的合成：一种通过不对称催化氢化的方法。第二部分。含α1的GABA（A）/苯并二氮杂receptor受体亚型的选择性配体的设计，合成和药理作用：位于-3和-6位的β-咔啉及其相应的二价配体的SAR研究。第三部分。重要生物遗传中间体，（+）-聚神经氨酸和（+）-聚神经氨酸醛，以及16-表-维西辛和Macusine A的首次对映体全合成。
6. Novel chloroquinoline derivatives incorporating biologically active benzenesulfonamide moiety: synthesis cytotoxic activity and molecular docking [O] . Mostafa M. Ghorab, Mansour S. Alsaid, Mohammed S. Al-Dosari, 2016

机译：新型的具有生物活性苯磺酰胺部分的氯喹啉衍生物：合成细胞毒活性和分子对接
7. An Improved Synthesis of Key Intermediate to the Formation of Selected Indolin-2-Ones Derivatives Incorporating Ultrasound and Deep Eutectic Solvent (DES) Blend of Techniques, for Some Biological Activities and Molecular Docking Studies [O] . Mohd Imran, Md. Afroz Bakht, Abida Khan, 2020

机译：一种改进的关键中间体与结合超声波和深的共晶溶剂（DES）混合技术的选择吲哚-2-衍生物的形成，用于一些生物活性和分子对接研究

An Improved Synthesis of Key Intermediate to the Formation of Selected Indolin-2-Ones Derivatives Incorporating Ultrasound and Deep Eutectic Solvent (DES) Blend of Techniques for Some Biological Activities and Molecular Docking Studies

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