Implication of Porphyromonas gingivalis in colitis and homeostasis of intestinal epithelium

摘要

Monitoring of colitic mice. ( ) Body weight loss and lethality of mice were monitored for 12 days. The body weight of each mouse at day 0 was calculated as 100%. Numbers in parentheses mean the percentage of dead mice. In ‘DSS + PBS’ group, 2 mice at day 11 and 1 mouse at day 12 died. In ‘DSS + LPS’ and ‘DSS +  LPS’ group, 1 mouse at day12 died, respectively. ( ) Disease activity index indicating colitis severity was scored at day 12. 6 mice per group were used. In ( ), -value significance was calculated by comparing other groups against (+) group (marked as +). **