Aged mice show an increased mortality after anesthesia with a standard dose of ketamine/xylazine

摘要

Mortality of young and aged mice after anesthesia with ketamine/xylazine. Kaplan-Meier curves of young mice (2 months) and aged mice (26 months) after intraperitoneal injection of 2 mg ketamine and 0.2 mg xylazine. 15.4% of the aged mice but none of the young mice died after anesthesia (log-rank test:  = 0.039)