Current progress in hepatic tissue regeneration by tissue engineering

摘要

Hepatic tissues from various sources such as human, porcine and rat underwent decellularization using detergents. Repopulation of the decellularized liver scaffold is performed through various routes. Decellularized liver scaffold is chopped to cubes or thin slices then recellularized by microinjection. Whole-organ reseeded by exerting negative pressure suction. Various cell types such as induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs) or liver progenitor cells (LPCs) are used for recellularization