Protocol: FeBRILe3 Project: protocol for a prospective pragmatic multisite observational study and safety evaluation assessing Fever Blood cultures and Readiness for discharge in Infants Less than 3 months old

摘要

The purpose of this observational study is to assess the safety and impact of the introduction of a clinical practice guideline (CPG) recommending early discharge of infants with fever without source who are at low risk of serious bacterial infection (SBI). We hypothesise that implementation of this guideline will be associated with a rate of unplanned readmission to hospital (within 7 days of discharge) which is similar (ie, non-inferior) to that observed under previous standard practice.