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Shared genetic architecture and casual relationship between leptin levels and type 2 diabetes: large-scale cross-trait meta-analysis and Mendelian randomization analysis

机译：瘦素水平与2型糖尿病之间共有的遗传结构和偶然关系：大规模跨特征荟萃分析和孟德尔随机分析

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摘要

We aimed to estimate genetic correlation, identify shared loci and test causality between leptin levels and type 2 diabetes (T2D).

机译：我们旨在评估遗传相关性，确定共享的基因座并测试瘦素水平与2型糖尿病（T2D）之间的因果关系。

著录项

期刊名称 BMJ Open Diabetes Research Care
作者
Xinpei Wang; Jinzhu Jia; Tao Huang;
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作者单位

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年(卷),期 2020(8),1
年度 2020
页码 -1
总页数 10
原文格式 PDF
正文语种
中图分类心血管疾病;
关键词
type 2 diabetes; leptin; genetic epidemiology; genetic association;

机译：2型糖尿病瘦素遗传流行病学遗传关联;

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3. Systematic Review and Meta-Analysis of Randomized Controlled Trials on the Effect of SGLT2 Inhibitor on Blood Leptin and Adiponectin Level in Patients with Type 2 Diabetes [J] . Wu Peili, Wen Weiheng, Li Jitong, Hormone and Metabolic Research . 2019,第8期

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4. Serum Leptin Levels in Patients with Hepatitis B: A Meta-analysis [C] . Qiong-yuan ZHANG, Xuan XU, Mei LUO, International Conference on Biological Sciences and Technology . 2018

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Shared genetic architecture and casual relationship between leptin levels and type 2 diabetes: large-scale cross-trait meta-analysis and Mendelian randomization analysis

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