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Management of urethral atrophy after implantation of artificial urinary sphincter: what are the weaknesses?

机译:人工尿道括约肌植入术后尿道萎缩的管理:有哪些缺点?

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摘要

The use of artificial urinary sphincter (AUS) for the treatment of stress urinary incontinence has become more prevalent, especially in the “prostate-specific antigen (PSA)-era”, when more patients are treated for localized prostate cancer. The first widely accepted device was the AMS 800, but since then, other devices have also entered the market. While efficacy has increased with improvements in technology and technique, and patient satisfaction is high, AUS implantation still has inherent risks and complications of any implant surgery, in addition to the unique challenges of urethral complications that may be associated with the cuff. Furthermore, the unique nature of the AUS, with a control pump, reservoir, balloon cuff, and connecting tubing, means that mechanical complications can also arise from these individual parts. This article aims to present and summarize the current literature on the management of complications of AUS, especially urethral atrophy. We conducted a literature search on PubMed from January 1990 to December 2018 on AUS complications and their management. We review the various potential complications and their management. AUS complications are either mechanical or nonmechanical complications. Mechanical complications usually involve malfunction of the AUS. Nonmechanical complications include infection, urethral atrophy, cuff erosion, and stricture. Challenges exist especially in the management of urethral atrophy, with both tandem implants, transcorporal cuffs, and cuff downsizing all postulated as potential remedies. Although complications from AUS implants are not common, knowledge of the management of these issues are crucial to ensure care for patients with these implants. Further studies are needed to further evaluate these techniques.
机译:当更多患者接受局部前列腺癌治疗时,使用人工尿道括约肌(AUS)治疗压力性尿失禁变得更加普遍,尤其是在“前列腺特异性抗原(PSA)时代”。第一个被广泛接受的设备是AMS 800,但此后,其他设备也进入了市场。尽管随着技术和技术的进步疗效有所提高,并且患者满意度很高,但是AUS植入术仍然存在固有的风险和任何植入术的并发症,此外还有与袖套相关的尿道并发症的独特挑战。此外,AUS的独特性,包括控制泵,储液器,气囊袖带和连接管,意味着这些单个零件也可能引起机械复杂性。本文旨在介绍和总结有关AUS并发症(尤其是尿道萎缩)管理的最新文献。我们从1990年1月至2018年12月在PubMed上进行了有关AUS并发症及其治疗的文献检索。我们回顾了各种潜在的并发症及其处理方法。 AUS并发症是机械性或非机械性并发症。机械并发症通常涉及AUS的故障。非机械并发症包括感染,尿道萎缩,袖套侵蚀和狭窄。挑战尤其存在于尿道萎缩的管理中,串联植入物,经体袖套和袖套缩小均被假定为可能的疗法。尽管AUS植入物的并发症并不常见,但对这些问题的管理知识对于确保对使用这些植入物的患者进行护理至关重要。需要进一步研究以进一步评估这些技术。

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