Physical exercise during exposure to 40-Hz light flicker improves cognitive functions in the 3xTg mouse model of Alzheimer’s disease

摘要

Effects of exercise under exposure to the 40-Hz light flicker on spatial learning and memory and long-term memory. The Morris water maze task for spatial learning ( ) and memory ( ) and step through task for long-term memory ( ). CON: wild-type, AD: 3xTg-AD, AD+40: 3xTg-AD and 40-Hz light flickering, AD+EX: 3xTg-AD and exercise, and AD+40+EX: 3xTg-AD and exercise in the 40-Hz light flickering group. Data are expressed as the mean ± standard error of the mean (SEM). *