Treatment with MDMA from P11–20 disrupts spatial learning and path integration learning in adolescent rats but only spatial learning in older rats

摘要

RationalePrevious studies in rats showed that postnatal day (P)11–20 exposure to ±3,4-methylenedioxymetham-phetamine (MDMA, ecstasy) causes learning and memory deficits in adulthood. The emergence and permanence of these learning deficits are currently unknown.