Waning Immunity to Varicella in Infants of Human Immunodeficiency Virus - Seropositive and Seronegative Mothers

摘要

Immunity to varicella in HIV- exposed and unexposed infants born to unvaccinated mothers, acquiring protective antibodies at birth declined to non-protective (<1:8) levels by 5 months of age. Thus infants become susceptible to varicella before 12 months, recommended time for varicella immunizations in the US. Vaccination of susceptible HIV- seronegative women in the post-partum period may be important to consider.