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University of Kentucky Sanders-Brown Healthy Brain Aging Volunteers: Donor Characteristics Procedures and Neuropathology

机译:肯塔基州大学桑德斯 - 棕色健康脑老化志愿者:供体特征程序和神经病理学

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摘要

Cognitively intact elderly research volunteers at the University of Kentucky have been recruited, followed longitudinally, and autopsied with extensive neuropathological evaluations since 1989. To date, the cohort has recruited 1,030 individuals with 552 participants being actively followed, 363 deceased, and 273 autopsied. An extensive database has been constructed with continuous updates that include textured clinical, neuropsychological, neuroimaging, and pathological information. The history, demographics, clinical observations, and pathological features of this research cohort are described. We also explain some of the evolving methodologies and the academic contributions that have been made due to this motivated group of older Kentuckians.
机译:认识地招募了肯塔基大学的老年人研究志愿者,随后纵向,自1989年以来一直综合。据日期,召开了第1,030名与552名参与者进行了363名死者,263名已故的人员招聘了1,030人。已经构建了广泛的数据库,其连续更新包括纹理临床,神经心理学,神经影像和病理信息。描述了该研究队列的历史,人口统计学,临床观察和病理特征。我们还解释了一些不断变化的方法和由于这个竞技老年肯塔基州的群体而作出的学术贡献。

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