MRI-Assessment of Tumor Perfusion and 3D Segmented Volume at Baseline During Treatment and at Tumor Progression in Children with Newly Diagnosed Diffuse Intrinsic Pontine Glioma

摘要

Background and PurposeDiffuse Intrinsic Pontine Glioma (DIPG) is among the most devastating brain tumors in children, necessitating the development of novel treatment strategies and advanced imaging markers such as perfusion to adequately monitor clinical trials. This study investigated tumor perfusion and 3D segmented tumor volume as predictive markers for outcome in children with newly diagnosed DIPG.