Pd(II)-catalyzed C-H Iodination Using Molecular I2 as the Sole Oxidant

摘要

Pd-catalyzed ortho-C–H iodination directed by a weakly coordinating amide auxiliary using I2 as the sole oxidant was developed. This reaction is compatible with a wide range of heterocycles including pyridines, imidazoles, oxazoles, thiazoles, isoxazoles and pyrazoles.