Purpose. Assessing the role of breast MRI compared to galactography in patients with unilateral bloody or serous-bloody nipple discharge. Materials and Methods. Retrospective study including 53 unilateral discharge patients who performed galactography and MRI. We evaluated the capability of both techniques in identifying pathology and distinguishing between nonmalignant and malignant lesions. Lesions BIRADS 1/2 underwent follow-up, while the histological examination after surgery has been the gold standard to assess pathology in lesions BIRADS 3/4/5. The ROC analysis was used to test diagnostic MRI and galactography ability. Results. After surgery and follow-up, 8 patients had no disease (15%), 23 papilloma (43%), 11 papillomatosis (21%), 5 ductal cancer in situ (10%), and 6 papillary carcinoma (11%) diagnoses. Both techniques presented 100% specificity; MRI sensitivity was 98% versus 49% of galactography. Considering MRI, we found a statistical association between mass enhancement and papilloma (P < 0.001; AUC 0.957; CI 0.888–1.025), ductal enhancement and papillomatosis (P < 0.001; AUC 0.790; CI 0.623–0.958), segmental enhancement and ductal cancer in situ (P = 0.007; AUC 0.750; CI 0.429–1.071), and linear enhancement and papillary cancer (P = 0.011). Conclusions. MRI is a valid tool to detect ductal pathologies in patients with suspicious bloody or serous-bloody discharge showing higher sensitivity and specificity compared to galactography.
展开▼
机译：目的。在单侧血性或浆液性乳头溢液患者中评估乳腺MRI与乳腺造影相比的作用。材料和方法。回顾性研究包括53位单侧出院的患者，他们进行了乳腺摄影和MRI检查。我们评估了这两种技术在识别病理学和区分非恶性和恶性病变方面的能力。对BIRADS 1/2病变进行了随访，而手术后的组织学检查已成为评估BIRADS 3/4/5病变病理的金标准。 ROC分析用于测试诊断性MRI和乳腺摄影能力。结果。手术和随访后，有8例患者无疾病（15％），23例乳头状瘤（43％），11例乳头状瘤病（21％），5例原位导管癌（10％）和6例乳头状癌（11％）被诊断。两种技术均具有100％的特异性。 MRI敏感性为98％，而银河造影为49％。考虑MRI，我们发现肿块增高与乳头状瘤（P <0.001; AUC 0.957; CI 0.888–1.025），导管增高和乳头状瘤病（P <0.001; AUC 0.790; CI 0.623–0.958），节段性增高与导管癌之间存在统计学联系原位（P = 0.007； AUC 0.750； CI 0.429–1.071），以及线性增强和乳头状癌（P = 0.011）。结论。 MRI是检测可疑血性或浆液性分泌物患者导管病变的有效工具，与半乳摄影相比，其显示出更高的敏感性和特异性。
展开▼
