Early cognitively-based functional limitations predict loss of independence in instrumental activities of daily living in older adults

摘要

ObjectivesOlder adults with early forms of neurodegenerative disease are at risk for functional disability, which is often defined by the loss of independence in instrumental activities of daily living (IADLs). The current study investigated the influence of mild changes in everyday functional abilities (referred to as functional limitations) on risk for development of incident functional disability.