Catalytic Enantioselective Functionalization of Unactivated Terminal Alkenes

摘要

>Terminal alkenes are readily available functional groups that appear in α-olefins produced by chemical industry, and they appear in the products of many contemporary synthetic reactions. While the organic transformations that apply to such alkenes are amongst the most studied reactions in all of chemical synthesis, the number of reactions that apply to nonactivated terminal alkenes in a catalytic enantioselective fashion is small in number. This Review highlights the cases where stereocontrol in catalytic reactions of 1-alkenes is high enough to be useful for asymmetric synthesis.