Effects of Combined Oral Contraceptives Depot Medroxyprogesterone Acetate and the Levonorgestrel-releasing Intrauterine System on the Vaginal Microbiome

摘要

OBJECTIVESPrior studies suggest that the composition of the vaginal microbiome may positively or negatively affect susceptibility to sexually transmitted infections (STI) and bacterial vaginosis (BV). Some female hormonal contraceptive methods also appear to positively or negatively influence STI transmission and BV. Therefore changes in the vaginal microbiome that are associated with different contraceptive methods may explain, in part, effects on STI transmission and BV.