Surveillance of adverse events after seasonal influenza vaccination in pregnant women and their infants in the Vaccine Adverse Event Reporting System July 2010 – May 2016

摘要

Introduction:Routine immunization of pregnant women with seasonal inactivated influenza vaccines (IIV) is recommended in all trimesters of pregnancy. A review of the Vaccine Adverse Event Reporting System (VAERS) during 1990–2009 did not find any unexpected patterns of pregnancy complications or fetal outcomes after administration of IIV or live attenuated influenza vaccines (LAIV). During 2009–2010 pandemic H1N1 vaccination campaign, a study noted that the numbers of VAERS reports from pregnant women who received the influenza A (H1N1) 2009 inactivated monovalent vaccine (N=288) increased compared to 1990–2009 seasonal IIV pregnancy reports (N=148).