PATH-52. UTILIZING NEXT GENERATION SEQUENCING REPORTS IN CLINICAL DECISION MAKING: REPORT FROM THE NATIONAL INSTITUTES OF HEALTH (NIH) NEURO-ONCOLOGY BRANCH (NOB) NATURAL HISTORY STUDY (NHS) PRIMARY BRAIN TUMOR PANEL (PBTP)

摘要

BACKGROUNDThe use of molecular diagnostics is an integral component of CNS cancer care. The NIH NOB PBTP includes 80 alterations (55 mutations/copy number variations and 25 gene fusions) identified as relevant to the primary CNS patient population. We have previously reported on the diagnostic utility. Identified therapeutic target results from the PBTP are reported here.