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Interface dosimetry for electronic brachytherapy intracavitary breast balloon applicators

机译:电子近距离放射治疗腔内乳房球囊涂药器的界面剂量

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摘要

In this study, we evaluate the attenuation of the dose due to barium‐impregnation in the region between the surface of an electronic brachytherapy (EBT) balloon applicator for accelerated partial breast irradiation (APBI) and the prescription point at 1 cm depth in tissue. To perform the study, depth dose curves were calculated using a general purpose multi‐particle transport code (FLUKA) for a range of balloon wall thicknesses with and without barium impregnation. Numerical data were verified with experimental readings using a parallel plate extrapolation ionization chamber for different wall thicknesses. Depth dose curves computed using both numerical and experimental methods show a 6.0% attenuation of the dose at the 1.0 cm prescription line due to the impregnation of barium in the balloon material, which agrees well with the manufacturer's specification. By applying this single attenuation factor, dose calculations throughout the entire planned volume are uniformly affected. However, at the balloon surface, attenuation on the order of 18.0% is observed. The AAPM TG‐43 source data currently incorporated in commercially‐available treatment planning systems do not account for the variable dose distributions attributable to balloon wall attenuation. Our results show that variable attenuation factors that may have clinical significance should be applied in order to determine near‐surface dose distributions when using barium impregnated balloons for intracavitary breast brachytherapy. Dose distributions at distances greater than 1 cm from the surface of the balloon appear to be accurately represented without further modification.PACS numbers: 87.53.Jw, 87.55.D‐, 87.55.d, 87.55.Qr, 87.55.K‐
机译:在这项研究中,我们评估了在电子近距离放射治疗(EBT)球囊涂药器表面以加速局部乳房照射(APBI)与组织中1 cm深度的处方点之间的区域中钡浸渍引起的剂量衰减。为了进行这项研究,使用通用多颗粒传输代码(FLUKA)计算了在有和没有钡浸渍的情况下,一系列球囊壁厚的深度剂量曲线。使用平行板外推电离室针对不同壁厚通过实验读数验证了数值数据。使用数值和实验方法计算的深度剂量曲线显示,由于气球材料中钡的浸入,在1.0厘米处方线处剂量减少了6.0%,这与制造商的规范非常吻合。通过应用此单个衰减因子,整个计划体积中的剂量计算将受到统一影响。然而,在球囊表面,观察到约18.0%的衰减。目前纳入市售治疗计划系统的AAPM TG-43源数据并未考虑到因球囊壁衰减而导致的剂量分布不均。我们的结果表明,当使用钡浸润的球囊进行腔内乳房近距离放射治疗时,应使用可能具有临床意义的可变衰减因子来确定近表面剂量分布。距离球囊表面大于1 cm的剂量分布似乎无需进一步修改即可准确表示.PACS编号:87.53.Jw,87.55.D‐,87.55.d,87.55.Qr,87.55.K‐

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