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The impact of continuously‐variable dose rate VMAT on beam stability MLC positioning and overall plan dosimetry

机译:连续可变剂量率VMAT对光束稳定性MLC定位和总体计划剂量的影响

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摘要

A recent control system update for Elekta linear accelerators includes the ability to deliver volumetric‐modulated arc therapy (VMAT) with continuously variable dose rate (CVDR), rather than a number of fixed binned dose rates (BDR). The capacity to select from a larger range of dose rates allows the linac to maintain higher gantry speeds, resulting in faster, smoother deliveries. The purpose of this study is to investigate two components of CVDR delivery — the increase in average dose rate and gantry speed, and a determination of their effects on beam stability, MLC positioning, and overall plan dosimetry. Initially, ten VMAT plans (5 prostate, 5 head and neck) were delivered to a Delta4 dosimetric phantom using both the BDR and CVDR systems. The plans were found to be dosimetrically robust using both delivery methods, although CVDR was observed to give higher gamma pass rates at the 2%/2 mm gamma level for prostates (p    0.01). For the dual arc head‐and‐neck plans, CVDR delivery resulted in improved pass rates at all gamma levels (2%/2 mm to 4%/4 mm) for individual arc verifications (p    0.01), but gave similar results to BDR when both arcs were combined. To investigate the impact of increased gantry speed on MLC positioning, a dynamic leaf‐tracking tool was developed using the electronic portal imaging device (EPID). Comparing the detected MLC positions to those expected from the plan, CVDR was observed to result in a larger mean error compared to BDR (0.13 cm and 0.06 cm, respectively, p    0.01). The EPID images were also used to monitor beam stability during delivery. It was found that the CVDR deliveries had a lower standard deviation of the gun‐target (GT) and transverse (AB) profiles (p    0.01). This study has determined that CVDR may offer a dosimetric advantage for VMAT plans. While the higher gantry speed of CVDR appears to increase deviations in MLC positioning, the relative effect on dosimetry is lower than the positive impact of a flatter and more stable beam profile.PACS numbers: 87.56.bd; 87.55.km; 87.55.Qr
机译:Elekta直线加速器的最新控制系统更新包括以连续可变剂量率(CVDR)而不是许多固定装仓剂量率(BDR)进行容积调制电弧治疗(VMAT)的能力。从更大剂量范围内进行选择的能力使直线加速器能够保持更高的龙门速度,从而实现更快,更顺畅的输送。这项研究的目的是研究CVDR输送的两个组成部分–平均剂量率和机架速度的增加,以及确定它们对射线束稳定性,MLC定位和总体计划剂量的影响。最初,使用BDR和CVDR系统将十个VMAT计划(5个前列腺,五个头和颈部)交付给Delta 4 剂量模型。虽然使用CVDR在前列腺的2%/ 2mm伽马水平下观察到了更高的伽马通过率,但发现这两种给药方法的剂量方案都具有鲁棒性(p <0.01)。对于双电弧头颈计划,CVDR的交付可在各个伽马水平(2%/ 2 mm至4%/ 4 mm)上提高单个电弧验证的通过率(p <0.01),但得出的结果与当两个弧合并时的BDR。为了研究门架速度增加对MLC定位的影响,使用电子门禁成像设备(EPID)开发了一种动态叶子跟踪工具。将检测到的MLC位置与计划中预期的位置进行比较,观察到CVDR导致的平均误差比BDR更大(分别为0.13 cm和0.06 cm,p <0.01)。 EPID图像还用于监控分娩期间的光束稳定性。发现CVDR的发射具有较低的枪靶(GT)和横向(AB)轮廓标准偏差(p <0.01)。这项研究已经确定CVDR可能为VMAT计划提供剂量学上的优势。尽管较高的CVDR机架速度似乎会增加MLC定位的偏差,但对剂量学的相对影响却比更平坦和更稳定的光束轮廓所产生的积极影响要小。PACS编号:87.56.bd; 87.55。公里; 87.55

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