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Multi-source and ontology-based retrieval engine for maize mutant phenotypes

机译:基于多源和本体的玉米突变表型检索引擎

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摘要

Model Organism Databases, including the various plant genome databases, collect and enable access to massive amounts of heterogeneous information, including sequence data, gene product information, images of mutant phenotypes, etc, as well as textual descriptions of many of these entities. While a variety of basic browsing and search capabilities are available to allow researchers to query and peruse the names and attributes of phenotypic data, next-generation search mechanisms that allow querying and ranking of text descriptions are much less common. In addition, the plant community needs an innovative way to leverage the existing links in these databases to search groups of text descriptions simultaneously. Furthermore, though much time and effort have been afforded to the development of plant-related ontologies, the knowledge embedded in these ontologies remains largely unused in available plant search mechanisms. Addressing these issues, we have developed a unique search engine for mutant phenotypes from MaizeGDB. This advanced search mechanism integrates various text description sources in MaizeGDB to aid a user in retrieving desired mutant phenotype information. Currently, descriptions of mutant phenotypes, loci and gene products are utilized collectively for each search, though expansion of the search mechanism to include other sources is straightforward. The retrieval engine, to our knowledge, is the first engine to exploit the content and structure of available domain ontologies, currently the Plant and Gene Ontologies, to expand and enrich retrieval results in major plant genomic databases.>Database URL:
机译:包括各种植物基因组数据库在内的模型有机体数据库收集并允许访问大量异质信息,包括序列数据,基因产物信息,突变表型的图像等,以及许多这些实体的文字描述。尽管可以使用各种基本的浏览和搜索功能来使研究人员查询和细读表型数据的名称和属性,但允许对文本描述进行查询和排名的下一代搜索机制却很少见。此外,工厂界需要一种创新的方式来利用这些数据库中的现有链接来同时搜索文本描述组。此外,尽管已经花费了大量时间和精力来开发与植物相关的本体,但是嵌入在这些本体中的知识在可用的植物搜索机制中仍未得到使用。为了解决这些问题,我们为MaizeGDB开发了一个独特的突变表型搜索引擎。这种先进的搜索机制在MaizeGDB中集成了各种文本描述源,以帮助用户检索所需的突变表型信息。目前,突变表型,基因座和基因产物的描述被用于每次搜索,尽管将搜索机制扩展到包括其他来源很简单。据我们所知,检索引擎是第一个利用可用领域本体(目前为植物本体和基因本体)的内容和结构来扩展和丰富主要植物基因组数据库中检索结果的引擎。>数据库URL:

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