首页> 美国卫生研究院文献>Journal of Applied Clinical Medical Physics >Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams
【2h】

Are simple IMRT beams more robust against MLC error? Exploring the impact of MLC errors on planar quality assurance and plan quality for different complexity beams

机译:简单的IMRT光束对MLC误差是否更坚固?探索MLC错误对不同复杂度光束的平面质量保证和计划质量的影响

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

This study investigated the impact of beam complexities on planar quality assurance and plan quality robustness by introducing MLC errors in intensity‐modulate radiation therapy. Forty patients' planar quality assurance (QA) plans were enrolled in this study, including 20 dynamic MLC (DMLC) IMRT plans and 20 static MLC (SMLC) IMRT plans. The total beam numbers were 150 and 160 for DMLC and SMLC, respectively. Six different magnitudes of MLC errors were introduced to these beams. Gamma pass rates were calculated by comparing error‐free fluence and error‐induced fluence. The plan quality variation was acquired by comparing PTV coverage. Eight complexity scores were calculated based on the beam fluence and the MLC sequence. The complexity scores include fractal dimension, monitor unit, modulation index, fluence map complexity, weighted average of field area, weighted average of field perimeter, and small aperture ratio (  5cm2 and  50 cm2). The Spearman's rank correlation coefficient was calculated to analyze the correlation between these scores and gamma pass rate and plan quality variation. For planar QA, the most significant complexity index was fractal dimension for DMLC (p = −0.40) and weighted segment area for SMLC (p = 0.27) at low magnitude MLC error. For plan quality, the most significant complexity index was weighted segment perimeter for DMLC (p = 0.56) and weighted segment area for SMLC (p = 0.497) at low magnitude MLC error. The sensitivity of planar QA was weakly associated with the field complexity with low magnitude MLC error, but the plan quality robustness was associated with beam complexity. Plans with simple beams were more robust to MLC error.PACS number(s): 87.55
机译:这项研究通过在强度调制放射治疗中引入MLC错误,研究了光束复杂度对平面质量保证和计划质量鲁棒性的影响。本研究纳入了40位患者的平面质量保证(QA)计划,包括20个动态MLC(DMLC)IMRT计划和20个静态MLC(SMLC)IMRT计划。 DMLC和SMLC的总光束数分别为150和160。将六种不同大小的MLC误差引入这些光束。伽玛通过率是通过比较无误通量和误导通量来计算的。计划质量差异是通过比较PTV覆盖范围获得的。基于波束通量和MLC序列计算了八个复杂度评分。复杂度分数包括分形维数,监视器单位,调制指数,注量图复杂度,场面积的加权平均值,场周的加权平均值和小孔径比(<5cm 2 和<50 cm 2 )。计算Spearman等级相关系数,以分析这些分数与伽玛通过率和计划质量变化之间的相关性。对于平面质量保证,最重要的复杂性指标是在低幅度MLC误差下DMLC的分形维数(p = -0.40)和SMLC的加权段面积(p = 0.27)。对于计划质量,最重要的复杂性指标是在低级MLC误差下DMLC的加权段周长(p = 0.56)和SMLC的加权段面积(p = 0.497)。平面QA的灵敏度与场复杂度弱相关,而MLC误差较小,但计划质量的鲁棒性与波束复杂度相关。带有简单梁的计划对MLC误差的鲁棒性更强.PACS编号:87.55

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号