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Lanthanide-Functionalized Hydrophilic Magnetic Hybrid Nanoparticles: Assembly Magnetic Behaviour and Photophysical Properties

机译:镧系元素官能的亲水磁性杂化纳米粒子:组装磁性行为和光物理性质。

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摘要

The lanthanide-functionalized multifunctional hybrid nanoparticles combining the superparamagnetic core and the luminescent europium complex were successfully designed and assembled via layer-by-layer strategy in this work. It is noted that the hybrid nanoparticles were modified by a hydrophilic polymer polyethyleneimine (PEI) through hydrogen bonding which bestowed excellent hydrophilicity and biocompatibility on this material. A bright-red luminescence was observed by fluorescence microscopy, revealing that these magnetic-luminescent nanoparticles were both colloidally and chemically stable in PBS solution. Therefore, the nanocomposite with magnetic resonance response and fluorescence probe property is considered to be of great potential in multi-modal bioimaging and diagnostic applications.Electronic supplementary materialThe online version of this article (doi:10.1186/s11671-016-1497-3) contains supplementary material, which is available to authorized users.
机译:在这项工作中,通过逐层策略成功设计并组装了结合超顺磁性核和发光euro络合物的镧系元素官能化多功能杂化纳米颗粒。值得注意的是,杂化纳米颗粒通过亲水聚合物聚乙烯亚胺(PEI)通过氢键进行了修饰,从而赋予了该材料优异的亲水性和生物相容性。通过荧光显微镜观察到亮红色的发光,表明这些磁致发光纳米颗粒在PBS溶液中既胶态又化学稳定。因此,具有磁共振响应和荧光探针性质的纳米复合材料被认为在多模式生物成像和诊断应用中具有巨大潜力。电子补充材料本文的在线版本(doi:10.1186 / s11671-016-1497-3)包含补充材料,授权用户可以使用。

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