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Development of a rotational set‐up correction device for stereotactic head radiation therapy: A performance evaluation

机译:开发用于立体定向放射治疗的旋转装置校正装置:性能评估

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摘要

We developed a new head supporting device to provide accurate correction of rotational setup during image‐guided radiation therapy (IGRT), evaluating its correction performance and the efficacy of dose distribution in stereotactic radiotherapy (SRT) using a helical tomotherapy (HT) system. The accuracy of rotational motion was measured using an electronic inclinometer; we compared device angles and measurement values from 0.0° to 3.0°. The correction accuracy was investigated based on the distance between rotational centers in the device and on megavoltage computed tomography (MVCT); the correction values were compared using distances in the range of 0.0–9.0 cm using a head phantom with a rotational error of 1.5°. For an SRT with a simultaneous integrated boost plan and a rotational error of 3.0° in yaw angle using a head phantom, and for a single‐isocenter SRT for multiple brain metastases in the data of three patients, dosimetric efficacy of the HT unit was evaluated for calculated dose distributions with MVCT after rotational correction. This device can correct pitch and yaw angles within 0.3° and can be corrected to within 0.5° for each rotational angle according to the result of MVCT correction regardless of the rotational center position. In the head phantom study, the device had a beneficial impact on rotational correction; D99% for the target improved by approximately 10% with rotational correction. Using patient data with the device, the mean difference based on the treatment planning data was 0.3% for D99% and −0.1% for coverage index to the target. Our rotational setup correction device has high efficacy, and can be used for IGRT.
机译:我们开发了一种新的头部支撑设备,可在图像引导放射治疗(IGRT)期间提供旋转设置的准确校正,评估其校正性能以及使用螺旋体层摄影(HT)系统在立体定向放射治疗(SRT)中的剂量分布功效。使用电子测斜仪测量旋转运动的精度;我们比较了设备角度和0.0°至3.0°的测量值。根据设备中旋转中心之间的距离和兆伏计算机断层扫描(MVCT)研究了校正精度;校正值是使用头部幻影在1.5-1.0°范围内使用0.0-9.0厘米范围内的距离进行比较的。对于具有同时集成的增强计划和使用头部幻影的偏航角旋转误差为3.0°的SRT,以及针对三名患者数据中发生多个脑转移的单等中心SRT,评估了HT单元的剂量学疗效校正后用MVCT计算的剂量分布。该装置可以根据MVCT校正的结果在0.3°内将俯仰角和偏航角校正在0.3°以内,并且可以针对每个旋转角在0.5°以内校正,而与旋转中心位置无关。在头部幻像研究中,该设备对旋转矫正产生了有益的影响。通过旋转校正,目标的D99%提高了约10%。使用该设备的患者数据,基于治疗计划数据的平均差异为D99%为0.3%,针对目标的覆盖率指数为-0.1%。我们的旋转设置校正装置具有很高的功效,可用于IGRT。

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