首页> 美国卫生研究院文献>Journal of Musculoskeletal Neuronal Interactions >Differences of bone mineral mass volumetric bone mineral density geometrical and structural parameters and derived strength of the tibia between premenopausal and postmenopausal women of different age groups: a peripheral Quantitative Computed Tomography (pQCT) study
【2h】

Differences of bone mineral mass volumetric bone mineral density geometrical and structural parameters and derived strength of the tibia between premenopausal and postmenopausal women of different age groups: a peripheral Quantitative Computed Tomography (pQCT) study

机译:不同年龄段的绝经前和绝经后女性之间的骨矿物质质量骨矿物质体积密度几何参数和胫骨强度的差异:外围定量计算机断层扫描(pQCT)研究

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Menopause constitutes a significant cause of bone loss, and it is currently debated whether bone mass is preserved or begins to decline substantially before that time in women. We used pQCT of the tibia to estimate differences of bone mineral mass, bone geometry and derived strength between premenopausal and postmenopausal Caucasian women of different age-groups per decade of age (20-79y). For each individual, we assessed total, trabecular and cortical bone mineral content (BMC, mg) and volumetric bone mineral density (BMD, mg/cm3); total and cortical cross-sectional areas (CSA, mm2); periosteal circumference (PERI_C, mm); endosteal circumference (ENDO_C, mm); mean cortical thickness (CRT_THK, mm); and Stress-Strain Index (SSI). Comparisons were made both between premenopausal (N=84) and postmenopausal (N=231) women as distinct groups, and among women of the different age-groups. Our results indicated that premenopausal women had significantly higher trabecular and cortical BMC and vBMD, with higher cortical CSA, CRT_THK and SSI than postmenopausal women. Moreover, significant differences of trabecular but not cortical BMC, vBMD or SSI were found between women of the younger (<48y) age-groups. PERI_C, ENDO_C displayed lower values in the 20-29y group and higher values in the 70-79y group, denoting significant differences of bone geometry with aging.
机译:更年期是造成骨质流失的重要原因,目前正在争论女性在此之前是否保留或大量减少骨量。我们使用胫骨的pQCT估算了每十年(20-79岁)不同年龄组的绝经前和绝经后白人妇女之间的骨矿物质质量,骨几何形状和衍生强度的差异。我们评估了每个人的总骨小梁和皮质骨矿物质含量(BMC,mg)和骨矿物质体积密度(BMD,mg / cm 3 );总和皮质截面积(CSA,mm 2 );骨膜周长(PERI_C,mm);骨内膜周长(ENDO_C,mm);平均皮层厚度(CRT_THK,mm);和应力应变指数(SSI)。比较了绝经前妇女(N = 84)和绝经后妇女(N = 231)作为不同的群体,以及不同年龄组的女性之间的比较。我们的结果表明,绝经前妇女的骨小梁和皮质BMC和vBMD明显高于绝经后妇女,其CSA,CRT_THK和SSI更高。此外,在年龄较小(<48岁)的女性之间,发现小梁的BMC,vBMD或SSI没有显着差异。 PERI_C和ENDO_C在20-29岁组中显示较低的值,而在70-79岁组中显示较高的值,表示随着年龄的增长,骨骼的几何形状存在显着差异。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号