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Technical Note: A benchtop cone-beam x-ray fluorescence computed tomography (XFCT) system with a high-power x-ray source and transmission CT imaging capability

机译：技术说明：具有高功率X射线源和透射CT成像功能的台式锥束X射线荧光计算机断层扫描（XFCT）系统

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摘要

Purpose:This report describes upgrades and performance characterization of an experimental benchtop cone-beam x-ray fluorescence computed tomography (XFCT) system capable of determining the spatial distribution and concentration of metal probes such as gold nanoparticles (GNPs). Specifically, a high-power (~3 kW) industrial x-ray source and transmission CT capability were deployed in the same platform under the cone-beam geometry.

机译：目的：本报告描述了实验台式锥形束X射线荧光计算机断层扫描（XFCT）系统的升级和性能表征，该系统能够确定金属探针（如金纳米颗粒（GNP））的空间分布和浓度。具体而言，在锥形束几何结构下的同一平台中部署了高功率（约3 kW）工业X射线源和透射CT功能。

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期刊名称 Medical Physics
作者
Nivedh Manohar; Francisco J. Reynoso; Sang Hyun Cho;
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作者单位

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年(卷),期 -1(45),10
年度 -1
页码 4652–4659
总页数 18
原文格式 PDF
正文语种
中图分类放射医学;影像诊断学;
关键词
x-ray fluorescence computed tomography gold nanoparticles preclinical imaging multimodal imaging;

机译：X射线荧光计算机断层扫描;金纳米颗粒;临床前成像;多峰成像;

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专利

1. Technical Note: A benchtop cone‐beam x‐ray fluorescence computed tomography (XFCT) system with a high‐power x‐ray source and transmission CT imaging capability [J] . Manohar Nivedh, Reynoso Francisco J., Cho Sang Hyun Medical Physics . 2018,第10期

机译：技术说明：具有高功率X射线源的台式锥形梁X射线荧光计算断层扫描（XFCT）系统和传输CT成像能力
2. Experimental demonstration of benchtop x-ray fluorescence computed tomography (XFCT) of gold nanoparticle-loaded objects using lead- and tin-filtered polychromatic cone-beams [J] . Physics in medicine and biology. . 2012,第23期

机译：使用铅和锡过滤的多色锥束对金纳米颗粒负载物体进行台式X射线荧光计算机断层扫描（XFCT）的实验演示
3. Preliminary Results On Benchtop X-Ray Fluorescence Computed Tomography (XFCT) Imaging of Gold Nanoparticle-Loaded Objects Using a Fully Spectroscopic Pixelated X-Ray Detector [J] . Ahmed M. F., Jayarathna S., ORyan L., Medical Physics . 2019,第6期

机译：基于Benchtop X射线荧光计算断层扫描（XFCT）使用全光谱像素X射线探测器的金纳米粒子加载物体成像的初步结果
4. Quality of micro-CT images acquired from simultaneous micro-CT and benchtop x-ray fluorescence computed tomography (XFCT): A preliminary Monte Carlo study [C] . Manohar Nivedh, Cho Sang Hyun 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference . 2013

机译：通过同时进行微型CT和台式X射线荧光计算机断层扫描（XFCT）获得的微型CT图像的质量：初步的蒙特卡洛研究
5. Computed tomography for the non-destructive imaging of cultural heritage: X-ray, gamma and neutron sources [D] . Nguyen, Hai-Yen 2011

机译：计算机断层扫描技术，用于文化遗产的无损成像：X射线，γ和中子源
6. Experimental demonstration of benchtop x-ray fluorescence computed tomography (XFCT) of gold nanoparticle-loaded objects using lead- and tin-filtered polychromatic cone-beams [O] . Bernard L. Jones, Nivedh Manohar, Francisco Reynoso, -1

机译：使用铅和锡过滤多色锥束金纳米颗粒加载的对象的台式X射线荧光计算机断层摄影（XFCT）的实验演示
7. A detector’s eye view (DEV)-based OSEM algorithm for benchtop x-ray fluorescence computed tomography (XFCT) image reconstruction [O] . Luzhen Deng, Md F Ahmed, Sandun Jayarathna, 2019

机译：基于Benchtop X射线荧光计算断层扫描（XFCT）图像重建的探测器的眼睛视图（DEV）基于OSEM算法
8. Comparison of X-Ray Computed Tomography, Through-Transmission Ultrasound, and Low-KV X-Ray Imaging for Characterizing Green-State Ceramics [R] . Roberts, R. A., Ellingson, W. A., Vannier, M. W. 1985

机译：用于表征绿态陶瓷的X射线计算机断层扫描，透射超声和低KV X射线成像的比较

Technical Note: A benchtop cone-beam x-ray fluorescence computed tomography (XFCT) system with a high-power x-ray source and transmission CT imaging capability

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