Passive and Oxymetazoline-Enhanced Delivery with a Lens Device: Pharmacokinetics and Efficacy Studies with Rabbits

机译：镜片装置的被动和羟甲唑啉增强递送：兔的药代动力学和功效研究

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摘要

PurposeThe aims of this study were to assess the trans-scleral delivery of dexamethasone phosphate (DexP) with a prototype lens device and a formulation comprising a vasoconstrictor and to determine the efficacy of this delivery system in treating experimentally induced uveitis in a rabbit model.

机译：目的这项研究的目的是评估原型透镜装置和包含血管收缩剂的制剂对地塞米松磷酸酯（DexP）的跨巩膜递送，并确定该递送系统在兔模型中治疗实验性葡萄膜炎的功效。

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期刊名称 Journal of Ocular Pharmacology and Therapeutics
作者
David J. Miller; S. Kevin Li; Anthony L. Tuitupou; Rajan P. Kochambilli; Kongnara Papangkorn; Donald C. Mix Jr.; William I. Higuchi; John W. Higuchi;
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作者单位

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年(卷),期 -1(24),4
年度 -1
页码 385–391
总页数 7
原文格式 PDF
正文语种
中图分类药学;眼科学;
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专利

1. Passive and oxymetazoline-enhanced delivery with a lens device: pharmacokinetics and efficacy studies with rabbits. [J] . Miller DJ, Li SK, Tuitupou AL, Journal of ocular pharmacology and therapeutics: The official journal of the Association for Ocular Pharmacology and Therapeutics . 2008,第4期

机译：镜片设备的被动和羟甲唑啉增强递送：兔的药代动力学和功效研究。
2. Passive and Oxymetazoline-Enhanced Delivery with a Lens Device: Pharmacokinetics and Efficacy Studies with Rabbits [J] . David J. Miller S. Kevin Li Anthony L. Tuitupou Rajan P. Kochambilli Kongnara Papangkorn Donald C. Mix Jr. William I. Higuchi John W. Higuchi. Journal of Ocular Pharmacology and Therapeutics . 2008,第4期

机译：镜片装置的被动和羟甲唑啉增强递送：兔的药代动力学和功效研究
3. Ocular pharmacokinetic study on baicalin in lens of rabbits following intragastric administration. [J] . Zhiyan J, Zhengzhong B, Liange J, Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie . 2010,第1期

机译：胃内给药后黄ical苷在兔晶状体中的眼药代动力学研究。
4. Trans-Scleral Ophthalmic Drug Delivery from Silicone-Based Devices:I. Long-term In-Vivo Studies in NZW Rabbits [C] . Yoseph Yaacobi, James Chastain, Lisa Lowseth, Annual meeting of the Society For Biomaterials . 2003

机译：基于硅酮的装置的跨巩膜眼科药物递送：I. NZW家兔的长期体内研究
5. Pharmacokinetics of intraarterial calcineurin inhibitor delivery to composite tissue: A study of regional and systemic advantages of intraarterial delivery of calcineurin inhibitors (cyclosporine and tacrolimus) to a vascularly isolated rabbit forelimb. [D] . Shirbacheh, Mansour V. 1999

机译：动脉钙调神经磷酸酶抑制剂向复合组织递送的药代动力学：钙调神经磷酸酶抑制剂（环孢素和他克莫司）向血管分离的兔前肢的动脉内递送的区域和全身优势的研究。
6. Nanoemulsion Based Vehicle for Effective Ocular Delivery of Moxifloxacin Using Experimental Design and Pharmacokinetic Study in Rabbits [O] . Jigar Shah, Anroop B. Nair, Shery Jacob, 2019

机译：实验设计和药代动力学研究基于纳米乳的莫西沙星有效眼部给药载体
7. Passive and Oxymetazoline-Enhanced Delivery with a Lens Device: Pharmacokinetics and Efficacy Studies with Rabbits [O] . Miller, David J., Li, S. Kevin, Tuitupou, Anthony L., 2008

机译：镜片装置的被动和羟甲唑啉增强递送：兔的药代动力学和功效研究
8. Aerospace Sensor Component and Subsystem Investigation And Innovation-2 Component Exploration and Development (ASCII-2 CED). Delivery Order 0002: Volume 3 - Reconfigurable Aperture Antenna Virtual Prototyping (General Techniques for De-Embedding RF Passive Devices) [R] . Buurma, A. W. , Rojas, R. G. 2005

机译：航空航天传感器组件和子系统调查与创新 - 2组件探索与开发（asCII-2 CED）。交付订单0002：第3卷 - 可重新配置的孔径天线虚拟原型（用于去嵌入RF无源器件的一般技术）

Passive and Oxymetazoline-Enhanced Delivery with a Lens Device: Pharmacokinetics and Efficacy Studies with Rabbits

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