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Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis

机译：Teglicar对肝肉碱棕榈酰转移酶1的选择性可逆抑制作用降低了糖异生并改善了葡萄糖稳态。

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摘要

OBJECTIVEWe have developed a new antihyperglycemic agent (teglicar) through the selective and reversible inhibition of the liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1).

机译：目的我们通过选择性和可逆地抑制肉毒碱棕榈酰转移酶1（L-CPT1）的肝同种型，开发了一种新的降血糖药（teglicar）。

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期刊名称 Diabetes
作者
Roberto Conti; Edoardo Mannucci; Pompeo Pessotto; Emanuela Tassoni; Paolo Carminati; Fabio Giannessi; Arduino Arduini;
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作者单位

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年(卷),期 2011(60),2
年度 2011
页码 644–651
总页数 8
原文格式 PDF
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中图分类基础医学;
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1. Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis [J] . Roberto Conti Edoardo Mannucci Pompeo Pessotto Emanuela Tassoni Paolo Carminati Fabio Giannessi Arduino Arduini Diabetes . 2011,第2期

机译：Teglicar对肝肉碱棕榈酰转移酶1的选择性可逆抑制作用降低了糖异生并改善了葡萄糖稳态。
2. Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis [J] . Roberto Conti, Edoardo Mannucci, Pompeo Pessotto, Diabetes . 2011,第2期

机译：Teglicar对肝肉碱棕榈酰转移酶1的选择性可逆抑制作用降低了糖异生并改善了葡萄糖稳态。
3. Roux-en-Y gastric bypass improves glucose homeostasis, reduces oxidative stress and inflammation in livers of obese rats and in Kupffer cells via an AMPK-dependent pathway [J] . Peng Yanhua, Li James Zongyu, You Min, Surgery . 2017,第1期

机译：Roux-Zh-Y胃旁路改善葡萄糖稳态，通过AMPK依赖性途径减少了肥胖大鼠和Kupffer细胞肝脏中的氧化应激和炎症
4. THE ROLE OF LIVER IN GLUCOSE HOMEOSTASIS: A SEMI-PHYSICAL MODEL [C] . Manuela Monsalve Velez, Laura Jimenez Giraldo Argentine Conference on Automatic Control . 2018

机译：肝脏在葡萄糖稳态中的作用：半物理模型
5. Does long-term protein phosphatase 2A inhibition in mice dysregulate peripheral glucose homeostasis, lower hepatic glycogen content, and impair insulin-mediated signal transduction in the liver? [D] . Lee, Juyeon. 2016

机译：小鼠长期蛋白质磷酸酶2A抑制作用是否会异常调节外周葡萄糖稳态，降低肝糖原含量并损害肝脏中胰岛素介导的信号转导？
6. Integrative and Translational Physiology: Integrative Aspects of Energy Homeostasis and Metabolic Diseases: High-protein diet selectively reduces fat mass and improves glucose tolerance in Western-type diet-induced obese rats [O] . Andreas Stengel, Miriam Goebel-Stengel, Lixin Wang, -1

机译：综合和转化生理：能量稳态和代谢性疾病的综合方面：高蛋白饮食选择性地减少了西方饮食引起的肥胖大鼠的脂肪量并改善了糖耐量
7. Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis [O] . Conti, Roberto, Mannucci, Edoardo, Pessotto, Pompeo, 2011

机译：Teglicar对肝肉碱棕榈酰转移酶1的选择性可逆抑制作用降低了糖异生并改善了葡萄糖稳态。

Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and Improves Glucose Homeostasis

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